Review on Phytochemicals for the Treatment of Kidney Stones

Authors

  • Sasikala Chinnappan Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia
  • Phang Zi Ying Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia
  • Tey Hui Ying Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia
  • Lai Chu Wen Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia
  • Ng Ru Yun Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia
  • Song Jia Xin Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia
  • Ravishankar Ram Mani Faculty of Pharmaceutical Sciences, UCSI University, Kuala Lumpur, Malaysia
  • Jithendra Panneerselvam School of Pharmacy, International Medical University, Kuala Lumpur, Malaysia
  • Venkatalakshmi Ranganathan Crescent School of Pharmacy, B.S. Abdur Rahman Crescent Institute of Science & Technology, Chennai, India

DOI:

https://doi.org/10.5530/ctbp.2023.4s.103%20

Keywords:

Urolithiasis, kidney stones, natural plants, treatment, mechanism of action, main constituents

Abstract

Urolithiasis, also known as kidney stones, is a common urinary tract problem that is caused by the deposition of hard crystals formed by mineral or salt accumulation in the urinary tract. It can cause pain and obstruct urine flow. Several studies have shown that certain natural plants and/or their constituents can help to treat kidney stones. The aim of this review is to review the natural plants used to treat the disease and investigate their pharmacokinetics profile, pharmacodynamic properties, and molecular mechanism of action in treating kidney stones. The study protocol was published in Web of Science, Scopus, PubMed, Embase, Cochrane Library and Google Scholar were searched up to May 2023. This review provided insight into identifying natural plants that can be used to treat urolithiasis. The report showed the primary underlying mechanism of these natural plants, as well as their isolated useful constituents. Our study showed that there are many natural plants that can treat urolithiasis. However, It is necessary to conduct research to assure the safety and effectiveness of these plants and their chemical compounds.

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Published

13-12-2023

How to Cite

Sasikala Chinnappan, Phang Zi Ying, Tey Hui Ying, Lai Chu Wen, Ng Ru Yun, Song Jia Xin, Ravishankar Ram Mani, Jithendra Panneerselvam, & Venkatalakshmi Ranganathan. (2023). Review on Phytochemicals for the Treatment of Kidney Stones. Current Trends in Biotechnology and Pharmacy, 17(4A (Supplement), 151–161. https://doi.org/10.5530/ctbp.2023.4s.103