Scientific Advancements in Stem Cell Therapy for Cervical Spinal Cord Injuries-A Bibliometric Perspective

Abstract

Spinal cord injuries, particularly in the cervical region, pose significant clinical challenges due to their severe neurological impact and limited treatment options. In recent years, stem cell therapy has emerged as a promising approach to promote regeneration and functional recovery. This bibliometric analysis aims to map global research trends related to stem cell therapy, cervical, and spinal cord injuries. Using data from major scientific databases, we examined publication outputs, citation patterns, and collaborative networks. Results show a sharp increase in publications over the past decade, with most of the research originating from the United States, China, and Europe. In the past two decades, the development of stem cells and regenerative medicine, as well as indepth research on the pathophysiology of spinal cord injury, has brought new hope for its treatment. Keyword co-occurrence and trend analysis reveal a strong focus on neural regeneration, transplantation techniques, and clinical trial development. The cervical spinal cord remains a focal point due to its vulnerability and impact on quality of life. Our findings highlight not only current scientific advancements but also gaps in translational research and international collaboration. This study provides a comprehensive overview of the literature, guiding future directions in regenerative medicine and cervical spinal cord injury treatment using stem cell therapy.