Extraction, chemical characterization and antibacterial potential of marine algae Galaxaura oblongata against clinically isolated human pathogens

Abstract

This study looked at the antibacterial efficacy of a methanol extract produced coming from G. Oblangata towards clinical isolated human pathogens. The chemical constituents of an extracts from methanol was examined by using phytochemicals and FTIR. Furthermore, methanol extract was tested for antibacterial activity against eleven human infections. At 100 μg/ml concentration, the methanol extract inhibited S. typhi with a maximal zone of 19mm. The MIC values for the methanolic extract were 100, 80, 100, 60, 100, 100, and 100 g/ml against infections caused by S. aureus, K. pneumoniae K. oxytoca, S. typhi, S. paratyphi, P. mirabilis, and S. pyogenes, respectively. The methanolic extract has MBC values of 100, 80, 100, 100, 60, 100, 100, and 100 μg/ml against strains of bacteria including S. typhi, S. aureus, K. pneumonia, E. coli, and S. paratyphi. These findings indicate that the extract of methanol from G. Oblangata is a good candidate for pharmaceutical research, opening the path for the development of powerful future antibiotics.